ABSTRACT
To determine the effectiveness and safety of elective termination of pregnancies from 56 days gestational age 2nd trimester in which ingestion of 20 mg tamoxifen for 4 days was followed by oral administration of 1 or 2 days of 800 micro g misoprostol. A clinical trial. Department of Obstetrics and Gynaecology, Nishtar Hospital, and Private setup, Multan. January 2009 to January 2010. A total of 50 patients were included in the trial on outdoor basis. Of the 17 subjects with a gestational age between 50 and 56 days. 15[88.2%] aborted their pregnancies. The mean duration of uterine bleeding in the group of women who aborted their pregnancies was 8.1 days with a range of 1-34 days. ln conclusion, the regimen of oral tamoxifen followed by oral administration of misoprostol was found to be an effective and rapid method to electively terminate early gestation of 8 weeks duration or less with no serious side effects.
ABSTRACT
To determine feto-maternal outcome and to identify factors associated with adverse obstetric outcome. This descriptive case series study was conducted in the Department of Obstetrics and Gynecology Unit lit. Nishtar Hospital, Multan. During the period from 18[th] July 2007 to 17[th] January 2008. One hundred patients who were admitted through emergency after a trial of labour by traditional birth attendants [TBAs], lady health visitors [LHVs] or doctors at home or private clinics were managed and followed in the department of gynecology and obstetrics Unit-II. Mean age of the patients was 27.28 +/- 5.13 years. Fever was the most common complication found in 69[69%] patients. Antepartum hemorrhage occurred in 22 [22%] cases. Postpartum hemorrhage complicated 46 [46%] pregnancies leading, to shock in 51 [51%] patients. Oligohydramnios was observed in 35 [35%] patients and uterine rupture in 5[5%] cases. There were 3 [3%] maternal deaths. Low Apgar score was observed in 36 [36%] patients. Meconium staining was common in 34 [34%] cases and 34 [34%] patients needed for hospitalization. Fetal growth restriction was found in 23 [23%] patients. There were 23 [23%] fetal deaths. Postpartum hemorrhage led to maternal and fetal complications in majority of the patients which was not handled